robaxin ® /robaxin ®-750 (methocarbamol tablets, USP), a carbamate derivative of guaifenesin, is a central nervous system (CNS) depressant with sedative and musculoskeletal relaxant properties
2009
Including: phenytoin (Dilantin) and trimethadione (Tridione)
It is noteworthy than many of the affected patients were elderly and were taking several potentially nephrotoxic drugs
If a patient has kidney stones with no underlying renal issues, then any OTC pain medication can be used to manage the pain symptoms associated Methocarbamol is a centrally acting muscle relaxant that is a carbamate derivative of guaifenesin (Liquibid, Mucinex, others)
Objective This study generated consensus on the nephrotoxic effect of 195 medications
rate; use lowest effective doses and shortest duration of concomitant tx: combo may incr
Antibiotics are one of the most common causes of drug-induced nephrotoxicity
Muscle relaxants are used to treat two different conditions: (1) spasticity from upper motor neuron syndromes as occurs in multiple sclerosis and (2) muscular pain or spasms from peripheral musculoskeletal diseases or injury such as low back pain
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Methocarbamol injection is sometimes used in the treatment of tetanus, (lockjaw) which causes painful tightening of the muscles
Besides, when nephrotoxicity from pharmacologic agents is further Pain Medications
Like cisplatin, methotrexate is one of the most widely used antineoplastic drugs
This review summarizes pathophysiological mechanisms of drug-induced nephrotoxicity, classes of nephrotoxic drugs, management, prevention, and diagnosis in clinics
Drug-induced nephrotoxicity in adults is approximately 14%–26% in prospective cohort studies of AKI, whereas 16% of hospitalized AKI is due to drugs in the Methocarbamol
6, 7 It is a guaiacol glyceryl ether
The pH is adjusted, when necessary, with hydrochloric acid and/or sodium hydroxide
In addition to drug–drug interactions, unexpected drug-induced organ toxicities also represent an important subset of adverse drug reactions, and may account for a significant proportion of fatal reactions to drugs, estimated to be ∼100 000 deaths per